As an old embedded systems and real-time guy, I have always worked with computer systems that are in some way tied to their environment. Simics has often been used to model such computer systems, inside of customer organizations. Which makes it a bit hard to show… however, recently I have cooked up a demo showing Simics simulating a computer system alongside a physical system.
I just put out a post on the Wind River blog, pointing to both a video of my own “water heater” demo and some other Youtube videos showing Simics integrated with simulations of the real world. A screenshot of my setup in action is shown on the side of this post.